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Cruises From Santa Cruz de Tenerife

Choose from 58 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Genoa, Lisbon, Madeira and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 196 departures available from four leading cruise lines.
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21 Days
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58 Cruises (196 Cruise Departures)
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 24 October 2025
Countries Visited: Spain, Portugal
INSIDE
$2,257
OCEANVIEW
$2,768
BALCONY
$3,627
SUITE
-
From 2,257
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,451
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 31 October 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,550
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
INSIDE
$2,883
OCEANVIEW
$3,899
BALCONY
$4,451
SUITE
$9,945
From 2,883
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,703
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,703
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,525
OCEANVIEW
$3,154
BALCONY
$3,756
SUITE
-
From 2,525
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2024 to Mar 2025
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$959
OCEANVIEW
$1,177
BALCONY
$1,850
SUITE
$2,771
From 959
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$969
BALCONY
$1,315
SUITE
$2,087
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,762
OCEANVIEW
$1,976
BALCONY
$2,657
SUITE
$4,744
From 1,762
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 24 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,029
OCEANVIEW
$1,247
BALCONY
$2,237
SUITE
$2,840
From 1,029
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,505
OCEANVIEW
$2,286
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
12 Day Mediterranean with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Oct 2024 to Oct 2024
Countries Visited: Spain, Portugal, France, Italy (+1 more), Morocco
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,615
SUITE
-
From 2,615
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$663
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 663
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,748
SUITE
$3,936
From 1,497
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,772
OCEANVIEW
$2,038
BALCONY
$2,621
SUITE
$4,353
From 1,772
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 06 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,372
SUITE
-
From 1,497
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$712
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 712
View Trip
13 Day Atlantic Sunsets with Oceania Cruises
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 17 November 2025
Countries Visited: Spain, Barbados, Antigua and Barbuda, Puerto Rico (+1 more), USA
Exclusive Deal
INSIDE
$4,190
OCEANVIEW
$5,031
BALCONY
$5,724
SUITE
$7,516
Save 2,030
From 4,190
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 20 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 14 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,309
OCEANVIEW
$3,978
BALCONY
$4,778
SUITE
-
From 3,309
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,705
OCEANVIEW
$3,402
BALCONY
$4,084
SUITE
-
From 2,705
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,603
OCEANVIEW
$1,821
BALCONY
$2,494
SUITE
$3,415
From 1,603
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,653
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$3,927
From 1,653
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,471
SUITE
$4,332
From 1,497
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$2,840
From 2,840
View Trip
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