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Panama Tours & Cruises Starting In December 2025

If you're looking at joining a tour to Panama in December 2025, we have 22 unique cruises, small group tours and adventures with 190 departures from the world's leading tour operators departing in December.
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Departures (December 2025)
< November 2025 January 2026 >
Duration
11 Days
28 Days
Types
Start & End Cities
Operators
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Price
$1,500pp
$124,495pp
Countries
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22 Trips (190 Trip Departures)
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Costa Rica, Panama
Limited Time Sale
Save 343
From 1,578
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Ships: Viking Neptune, Viking Sky
Departures: Oct 2024 to Dec 2025
Countries Visited: USA, Mexico, Colombia, Panama (+1 more), Costa Rica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$19,795
Save 1,110
From 9,895
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (2)

17 Days (16 Nights) San Francisco to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Jan 2025 to Dec 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
Exclusive Deal
INSIDE
$2,867
OCEANVIEW
$3,130
BALCONY
$4,330
SUITE
$5,876
From 2,867
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (2)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 23 December 2025
Countries Visited: USA, Aruba, Panama, Costa Rica (+2 more), Nicaragua, Mexico
Exclusive Deal
INSIDE
$3,265
OCEANVIEW
$3,571
BALCONY
$4,722
SUITE
$7,027
From 3,265
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$5,440
SUITE
$8,410
Save 1,230
From 5,440
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: Panama, Costa Rica, Honduras, Belize (+2 more), Mexico, USA
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$5,638
SUITE
$8,905
Save 1,091
From 5,638
View Trip
28 Day Amazing Central America with Intrepid Travel
Tour

28 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua (+2 more), Costa Rica, Panama
Limited Time Sale
Save 763
From 3,480
View Trip
16 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Los Angeles to Miami
Ships: Norwegian Bliss, Norwegian Encore (+1 more), Norwegian Joy
Departures: Oct 2025 to Feb 2026
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
Exclusive Solo Offer
INSIDE
$3,586
OCEANVIEW
$4,580
BALCONY
$5,139
SUITE
$5,903
From 3,586
View Trip
12 Day Panama Canal & Perfect Day Holiday with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 22 December 2025
Countries Visited: USA, Colombia, Panama, Aruba (+2 more), Curacao, Bahamas
Exclusive Offer
INSIDE
$3,473
OCEANVIEW
$3,982
BALCONY
$4,366
SUITE
$12,195
Save 3,872
From 3,473
View Trip
15 Day Panama Canal & Central America with Viking Cruises
Cruise
 (4)

15 Days (14 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2024 to Feb 2026
Countries Visited: USA, Jamaica, Panama, Costa Rica (+3 more), Honduras, Belize, Mexico
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$7,420
SUITE
$12,667
Save 1,099
From 7,420
View Trip
13 Day Panama Canal Sunfarer with Holland America
Cruise
 (2)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Oct 2024 to Mar 2026
Countries Visited: USA, Bahamas, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
Have It All Offer
INSIDE
$3,212
OCEANVIEW
$3,806
BALCONY
$4,845
SUITE
$5,815
From 3,212
View Trip
13 Day Panama Canal Sunfarer with Holland America
Cruise
 (2)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Nov 2025 to Dec 2025
Countries Visited: USA, Bahamas, Curacao, Colombia (+3 more), Panama, Costa Rica, Jamaica
Have It All Offer
INSIDE
$3,677
OCEANVIEW
$4,618
BALCONY
$5,014
SUITE
$6,449
From 3,677
View Trip
12 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ship: Norwegian Pearl
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Jamaica, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
Exclusive Solo Offer
INSIDE
$2,938
OCEANVIEW
$3,687
BALCONY
$5,384
SUITE
$5,689
From 2,938
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Nov 2025 to Dec 2025
Countries Visited: USA, Jamaica, Aruba, Colombia (+3 more), Panama, Costa Rica, Honduras
Early Booking Offer
INSIDE
$2,088
OCEANVIEW
$2,375
BALCONY
$2,701
SUITE
$3,800
From 2,088
View Trip
11 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Panama City
Ship: Norwegian Jade
Departure: 12 December 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
INSIDE
$2,683
OCEANVIEW
$3,142
BALCONY
$4,365
SUITE
$4,748
From 2,683
View Trip
12 Day Central America with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Miami to Miami
Ships: Norwegian Gem, Norwegian Jade
Departures: Nov 2024 to Dec 2025
Countries Visited: USA, Cayman Islands, Colombia, Panama (+3 more), Costa Rica, Belize, Mexico
INSIDE
$2,884
OCEANVIEW
$3,343
BALCONY
$5,022
SUITE
$5,527
From 2,884
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ships: Caribbean Princess, Emerald Princess
Departures: Jan 2025 to Jan 2026
Countries Visited: USA, Aruba, Bonaire, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
Exclusive Deal
INSIDE
$2,074
OCEANVIEW
$2,123
BALCONY
$3,222
SUITE
$4,143
From 2,074
View Trip
13 Day Panama Canal with Costa Rica & Caribbean Holiday with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 December 2025
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
Exclusive Deal
INSIDE
$2,296
OCEANVIEW
$2,457
BALCONY
$3,445
SUITE
$4,366
From 2,296
View Trip
22 Day Panama Canal Sunfarer & Southern Caribbean Seafarer with Holland America
Cruise
 (2)

22 Days (21 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Oct 2025 to Mar 2026
Countries Visited: USA, Bahamas, Curacao, Colombia (+5 more), Panama, Costa Rica, Cayman Islands, Bonaire, Aruba
Have It All Offer
INSIDE
$5,986
OCEANVIEW
$7,322
BALCONY
$7,916
SUITE
$10,094
From 5,986
View Trip
22 Day Panama Canal & Southern Caribbean Holiday with Holland America
Cruise
 (2)

22 Days (21 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departure: 28 December 2025
Countries Visited: USA, Bahamas, Curacao, Colombia (+5 more), Panama, Costa Rica, Jamaica, Bonaire, Aruba
Have It All Offer
INSIDE
$6,827
OCEANVIEW
$8,163
BALCONY
$8,955
SUITE
$11,381
From 6,827
View Trip
22 Day Southern Caribbean & Panama Canal: ABC Islands with Holland America
Cruise
 (2)

22 Days (21 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Nov 2025 to Dec 2025
Countries Visited: USA, Curacao, Bonaire, Aruba (+5 more), Bahamas, Colombia, Panama, Costa Rica, Jamaica
Have It All Offer
INSIDE
$5,986
OCEANVIEW
$7,322
BALCONY
$7,916
SUITE
$10,094
From 5,986
View Trip
14 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

14 Days (13 Nights) Panama City to New York
Ship: Norwegian Jade
Departure: 22 December 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+5 more), Saint Lucia, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
INSIDE
$4,008
OCEANVIEW
$4,774
BALCONY
$6,685
SUITE
$7,832
From 4,008
View Trip
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