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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 455 unique cruise itineraries from 10 leading cruise lines. May is the most popular month to join a luxury cruise in the Mediterranean with 542 departures starting between June 2024 and April 2027.
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455 Cruises (542 Cruise Departures)
12 Day Mediterranean Mosaic with Regent Seven Seas
Cruise

12 Days (11 Nights) Monte Carlo to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 21 June 2025
Countries Visited: Monaco, France, Spain, Tunisia (+2 more), Malta, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,349
SUITE
$15,904
Save 6,631
From 14,349
View Trip
12 Day Culture and Islands of the Mediterranean with Ponant
Cruise

12 Days (11 Nights) Barcelona to Valletta
Cruise Line: Ponant
Ship: L'Austral
Departure: 26 April 2025
Countries Visited: Spain, Sardinia, Sicily, Italy (+1 more), Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
$9,669
BALCONY
$10,198
SUITE
$19,185
Save 181
From 9,669
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,734
BALCONY
$1,932
SUITE
$4,258
From 1,486
View Trip
11 Day Heart Of The Mediterranean with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 23 April 2025
Countries Visited: Spain, France, Italy, Sicily (+3 more), Tunisia, Malta, Greece
Exclusive Solo OfferExclusive Deal
INSIDE
-
OCEANVIEW
$10,139
BALCONY
$12,356
SUITE
$13,832
Save 7,691
From 10,139
View Trip
19 Day Andalusian Nights & Monte Carlo Masters with Seabourn
Cruise

19 Days (18 Nights) Lisbon to Rome
Cruise Line: Seabourn
Ship: Venture
Departure: 26 March 2025
Countries Visited: Portugal, Spain, Morocco, France (+2 more), Monaco, Italy
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$17,946
SUITE
$43,443
From 17,946
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
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12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,432
SUITE
-
From 24,432
View Trip
11 Day Azure Mediterranean with Oceania Cruises
Cruise

11 Days (10 Nights) Monte Carlo to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 August 2024
Countries Visited: Monaco, Italy, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,537
SUITE
-
Save 2,123
From 13,537
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Countries Visited: Egypt, Jordan, Israel, Cyprus (+2 more), Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,355
BALCONY
-
SUITE
$24,220
Save 6,685
From 18,355
View Trip
12 Day Lisbon to Barcelona with Silversea
Cruise

12 Days (11 Nights) Lisbon to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 April 2025
Countries Visited: Portugal, Spain, Morocco, Gibraltar
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,206
Save 894
From 14,206
View Trip
15 Day Mediterranean Rivieras & The Calanques with Seabourn
Cruise

15 Days (14 Nights) Monte Carlo to Monte Carlo
Cruise Line: Seabourn
Ship: Sojourn
Departure: 12 October 2024
Countries Visited: Monaco, Italy, France, Spain (+1 more), Sardinia
More Moments On Us Offer
INSIDE
-
OCEANVIEW
$10,408
BALCONY
-
SUITE
$22,882
From 10,408
View Trip
9 Day Springtime Rivieras with Oceania Cruises
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 May 2025
Countries Visited: Italy, Corsica, France, Spain
Cabin Upgrade Offer
INSIDE
$4,734
OCEANVIEW
$5,417
BALCONY
$6,338
SUITE
$8,545
From 4,734
View Trip
9 Day A Journey To Soulful Sicily And Southern Greece with Explora Journeys
Cruise

9 Days (8 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta
Exclusive DealUnique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$7,573
SUITE
$8,791
From 7,573
View Trip
8 Day Mediterranean Escapade: Spain & the French Riviera with Scenic
Cruise

8 Days (7 Nights) Barcelona to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 29 April 2025
Countries Visited: Spain, France, Corsica
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,351
SUITE
$14,068
Save 2,094
From 9,351
View Trip
8 Day A Journey Of Riviera Reveries And Italian Icons with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 26 August 2024
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Exclusive DealUnique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$6,816
SUITE
$8,286
From 6,816
View Trip
11 Day Andalusian Nights: Spotlight On Seville with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Seabourn
Ship: Venture
Departure: 20 April 2025
Countries Visited: Spain, France, Morocco, Portugal
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$11,036
SUITE
$26,941
From 11,036
View Trip
21 Day Lisbon to Lisbon with Silversea
Cruise

21 Days (20 Nights) Lisbon to Lisbon
Cruise Line: Silversea
Ship: Silver Moon
Departure: 02 November 2024
Countries Visited: Portugal, Morocco, Gibraltar, Spain (+4 more), Tunisia, Malta, Sicily, Sardinia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$19,404
BALCONY
$22,473
SUITE
$37,719
From 19,404
View Trip
8 Day French Riviera & the Catalan Coastline with Scenic
Cruise

8 Days (7 Nights) Nice to Barcelona
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: May 2025 to Apr 2026
Countries Visited: France, Corsica, Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,192
SUITE
$14,563
Save 3,103
From 10,192
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 May 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+4 more), Greece, Montenegro, Croatia, Malta
Exclusive Deal
INSIDE
$3,521
OCEANVIEW
$3,867
BALCONY
$4,560
SUITE
$12,183
From 3,521
View Trip
12 Day Antiquity To Anatolia with Oceania Cruises
Cruise

12 Days (11 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,924
SUITE
$10,844
Save 2,056
From 6,924
View Trip
8 Day Iconic Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 09 June 2025
Countries Visited: Greece, Italy, Monaco, France (+1 more), Spain
Exclusive Deal
INSIDE
$4,190
OCEANVIEW
$4,952
BALCONY
$5,794
SUITE
$7,457
Save 2,030
From 4,190
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Moon
Departure: 01 October 2024
Countries Visited: France, Italy, Monaco, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,840
BALCONY
$13,414
SUITE
$33,016
Save 860
From 10,840
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy (+2 more), Sardinia, Sicily
Exclusive Deal
INSIDE
$2,875
OCEANVIEW
$2,974
BALCONY
$3,469
SUITE
$8,221
From 2,875
View Trip
31 Day Tyrrhenian Treasures & Mediterranean Jewels with Seabourn
Cruise

31 Days (30 Nights) Monte Carlo to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 25 April 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+5 more), Corsica, France, Spain, Sardinia, Tunisia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$25,610
SUITE
$44,207
From 25,610
View Trip
10 Day Exquisite Mediterranean with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 05 September 2024
Countries Visited: Italy, Sicily, Greece, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,315
SUITE
$14,790
Save 4,225
From 13,315
View Trip
8 Day Italy And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy
Exclusive Deal
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$1,932
SUITE
$4,654
From 1,585
View Trip
11 Day Mediterranean Overture with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Monaco, Italy (+2 more), Corsica, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,761
SUITE
$15,913
From 8,761
View Trip
8 Day Mediterranean Marvels & Matches: Barcelona Open with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$7,749
SUITE
$18,436
From 7,749
View Trip
11 Day Wine Lovers Dream with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 13 September 2025
Countries Visited: Spain, France, Italy, Sicily (+2 more), Turkey, Greece
Exclusive DealExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,248
BALCONY
$12,208
SUITE
$14,129
Save 7,682
From 9,248
View Trip
Results: 121-150 of 455

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